Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678382 | 0.91 | TLR7 (0.43) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8680399 | 0.91 | GCGR (0.39) | GCGRTLR7L3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL8678204 | 0.86 | CYP1A2 (0.38) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8676900 | 0.86 | L3MBTL1 (0.43) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8678060 | 0.85 | TLR7 (0.42) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8679202 | 0.85 | KDM4E (0.39) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8677290 | 0.85 | TLR7 (0.43) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8678398 | 0.84 | KDM4E (0.44) | L3MBTL1CYP2C9CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8678115 | 0.83 | TLR7 (0.40) | TLR7L3MBTL1CYP2C9LMNASMN1; SMN2 | |
| SCHEMBL8137227 | 0.82 | CYP1A2 (0.43) | TLR7L3MBTL1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| CN-1109879-A | 2-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1995-10-11 | — | — | CN | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |