⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201019 | 0.67 | — | — | |
| SCHEMBL16269303 | 0.67 | — | — | |
| SCHEMBL18986435 | 0.61 | — | — | |
| SCHEMBL486270 | 0.58 | — | — | |
| SCHEMBL6488288 | 0.57 | — | — | |
| SCHEMBL10369835 | 0.57 | — | — | |
| SCHEMBL290757 | 0.53 | — | — | |
| SCHEMBL447169 | 0.53 | — | — | |
| SCHEMBL1555131 | 0.51 | — | — | |
| SCHEMBL2547201 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100048-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-10-16 | — | — | US | disclosed |
| EP-2621914-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2016-12-28 | — | — | EP | disclosed |
| US-20160194320-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | ABBVIE DEUTSCHLAND (DE) | 2016-07-07 | — | — | US | disclosed |
| US-9266855-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20160016932-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-01-21 | — | — | US | disclosed |
| EP-2621914-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | Abbott GmbH & Co. KG (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2443109-A1 | TRIAZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443099-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443097-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010122169-A1 | 5-MERCAPTO- [1,2, 4] TRIAZOLE COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTICAL USES | BASF SE (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010122167-A1 | 5 -MERCAPTO- [1, 2, 4] TRIAZOLYLMETHYL-CYCLOPENTANOL COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTICAL USES | BASF SE (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010122171-A1 | 5-HETEROARYLMETHYL-I- (B-MERCAPTO- [1,2, 4 -TRIAZOLYLMETHYL) -CYCLOPENTANOL AS FUNGICIDES | BASF SE (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010070035-A1 | THIOUREA COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2010-06-24 | — | — | WO | disclosed |
| US-20090264447-A1 | Pyrimidine compounds for combating pathogenic fungi and cancer | BASF SE (DE) | 2009-10-22 | — | — | US | disclosed |
| EP-2049498-A1 | PYRIMIDINE COMPOUNDS FOR COMBATING PATHOGENIC FUNGI AND CANCER | BASF SE (DE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008015250-A1 | PYRIMIDINE COMPOUNDS FOR COMBATING PATHOGENIC FUNGI AND CANCER | BASF SE (DE) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008012292-A1 | LIQUID CRYSTALLINE BLEND | BASF SE (DE) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007147829-A1 | AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |