Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446929 | 0.90 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL468901 | 0.90 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL30526285 | 0.90 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL6026003 | 0.90 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| Acetic Acid SCHEMBL28406175 | 0.89 | FOLH1 (0.48) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| Hydrochloric Acid SCHEMBL4422480 | 0.89 | FOLH1 (0.48) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| Water SCHEMBL29401510 | 0.89 | FOLH1 (0.48) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL9438405 | 0.89 | FOLH1 (0.48) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL12971304 | 0.88 | C3AR1 (0.43) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT | |
| SCHEMBL29005731 | 0.88 | C3AR1 (0.43) | FOLH1C3AR1NOD1SMN1; SMN2GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154585-B1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2022-02-23 | — | — | EP | claimed |
| US-20220040298-A1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | DARTMOUTH COLLEGE (US) | 2022-02-10 | — | — | US | claimed |
| CN-107073109-B | Use of VISTA agonists and antagonists to inhibit or enhance humoral immunity | 凯西·A·格林 | 2021-08-06 | — | — | CN | claimed |
| US-20170119877-A1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | IMMUNEXT INC. (US) | 2017-05-04 | — | — | US | claimed |
| EP-3154585-A2 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | Green, Kathy A. (US) | 2017-04-19 | — | — | EP | claimed |
| WO-2015191881-A9 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2016-04-21 | — | — | WO | claimed |
| WO-2015191881-A2 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2015-12-17 | — | — | WO | claimed |
| US-5470847-A | Contraceptives by inhibiting ovulation | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-11-28 | — | — | US | claimed |
| EP-3154585-B1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20220040298-A1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | DARTMOUTH COLLEGE (US) | 2022-02-10 | — | — | US | disclosed |
| US-11123426-B2 | Use of vista agonists and antagonists to suppress or enhance humoral immunity | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-09-21 | — | — | US | disclosed |
| CN-107073109-B | Use of VISTA agonists and antagonists to inhibit or enhance humoral immunity | 凯西·A·格林 | 2021-08-06 | — | — | CN | disclosed |
| US-20170119877-A1 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | IMMUNEXT INC. (US) | 2017-05-04 | — | — | US | disclosed |
| EP-3154585-A2 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | Green, Kathy A. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191881-A9 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2016-04-21 | — | — | WO | disclosed |
| WO-2015191881-A2 | USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY | GREEN KATHY A (US) | 2015-12-17 | — | — | WO | disclosed |
| US-5721278-A | Ovulation control by regulating nitric oxide levels | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-02-24 | — | — | US | disclosed |
| US-5643944-A | ADMINISTERING ARGININE, SODIUM NITROPRUSSIDE, NITROGLYCERINE AND IDOSORBIDE MONO OR DINITRATE MIXTURE TO STIMULATE OVULATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-07-01 | — | — | US | disclosed |
| US-5470847-A | Contraceptives by inhibiting ovulation | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-11-28 | — | — | US | disclosed |
| WO-1995015753-A1 | OVULATION CONTROL BY REGULATING NITRIC OXIDE LEVELS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-06-15 | — | — | WO | disclosed |