SCHEMBL8679014

SCHEMBL8679014

Cc1ccc(-c2ccccc2)c(C(C)C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.46
CYP2A6 P11509 2/20 0.39
CYP2B6 P20813 1/20 0.39
LMNA P02545 5/20 0.36
ALOX5 P09917 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
METAP2 P50579 1/20 0.35
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34
PTGS1 P23219 3/20 0.33
MEN1 O00255 2/20 0.33
TSHR P16473 2/20 0.33
PTGS2 P35354 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 2/20 0.33
FABP2 P12104 1/20 0.33
AKR1C4 P17516 1/20 0.33
ADRA2B P18089 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680517 0.86 ESR2 (0.42) ESR2CYP2A6CYP2B6LMNAALOX5
SCHEMBL11204134 0.83 ESR2 (0.38) ESR2CYP2A6CYP2B6LMNAPDCD1
SCHEMBL6838848 0.83 CDC25A (0.41) ESR2CYP2A6CYP2B6LMNAALOX5
SCHEMBL6546686 0.78 PDCD1 (0.41) ESR2CYP2A6CYP2B6PDCD1CD274
SCHEMBL28423706 0.76 CDC25A (0.44) CYP2A6CYP2B6PDCD1CD274CDC25A
SCHEMBL30804714 0.76 ESR2 (0.48) ESR2CYP2A6CYP2B6ALOX5PDCD1
SCHEMBL2400343 0.76 ESR2 (0.48) ESR2CYP2A6CYP2B6ALOX5PDCD1
SCHEMBL6067573 0.74 PDCD1 (0.39) ESR2CYP2A6CYP2B6LMNAALOX5
SCHEMBL11203836 0.74 CD274 (0.37) ESR2CYP2A6CYP2B6PDCD1CD274
Hydrochloric Acid SCHEMBL25292717 0.74 ESR2 (0.47) ESR2CYP2A6CYP2B6ALOX5PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed