SCHEMBL6067573

SCHEMBL6067573

Cc1c(-c2ccccc2)ccc(I)c1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
ESR2 Q92731 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
PTGS1 P23219 3/20 0.33
MEN1 O00255 2/20 0.33
PTGS2 P35354 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
FABP2 P12104 1/20 0.33
TSHR P16473 1/20 0.33
AKR1C4 P17516 1/20 0.33
ADRA2B P18089 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838848 0.77 CDC25A (0.41) ESR2CYP2A6CYP2B6CDC25ACDC25B
SCHEMBL8679014 0.74 ESR2 (0.46) PDCD1CD274ESR2PARP10PARP11
SCHEMBL9792869 0.73 PDCD1 (0.54) PDCD1CD274ESR2PARP10PARP11
SCHEMBL8680517 0.72 ESR2 (0.42) PDCD1CD274ESR2CYP2A6CYP2B6
SCHEMBL16554648 0.72 PDCD1 (0.42) PDCD1CD274ESR2PARP10PARP11
SCHEMBL28371947 0.72 KDM4E (0.32) PTGS1PTGS2KMT2ALMNATSHR
SCHEMBL24051152 0.71 PDCD1 (0.53) PDCD1CD274ESR2PARP10PARP11
SCHEMBL24570750 0.71 ESR2 (0.45) PDCD1CD274ESR2PARP10PARP11
SCHEMBL28139610 0.71 LMNA (0.45) PTGS1MEN1PTGS2KMT2ALMNA
SCHEMBL28423706 0.70 CDC25A (0.44) PDCD1CD274CYP2A6CYP2B6CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3114148-B1 LIGHT INDUCED FREE RADICAL AND/OR CATIONIC PHOTOPOLYMERIZATION METHOD UNIV HAUTE ALSACE (FR) 2019-10-09 EP disclosed
US-10266616-B2 Light induced free radical and/or cationic photopolymerization method UNIVERSITÉ DE HAUTE-ALSACE (FR) 2019-04-23 US disclosed
US-20170073436-A1 LIGHT INDUCED FREE RADICAL AND/OR CATIONIC PHOTOPOLYMERIZATION METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2017-03-16 US disclosed
EP-3114148-A1 LIGHT INDUCED FREE RADICAL AND/OR CATIONIC PHOTOPOLYMERIZATION METHOD Université de Haute Alsace (FR) 2017-01-11 EP disclosed
WO-2015132295-A1 LIGHT INDUCED FREE RADICAL AND/OR CATIONIC PHOTOPOLYMERIZATION METHOD UNIVERSITÉ DE HAUTE-ALSACE (FR) 2015-09-11 WO disclosed
EP-2915822-A1 Light induced free radical and/or cationic photopolymerization method Université de Haute Alsace (FR) 2015-09-09 EP disclosed
US-20060233510-A1 OPTICAL FIBER ARRAY HATAKENSAKU CO., LTD. (JP) 2006-10-19 US disclosed