Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842938 | 0.82 | ERN1 (0.56) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL207231 | 0.80 | ERN1 (0.50) | MAPK1MEN1KMT2AALDH1A1PRKDC | |
| SCHEMBL10981231 | 0.80 | MAPK1 (0.50) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL31503831 | 0.80 | MAPK1 (0.50) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL8679011 | 0.78 | MAPK1 (0.49) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL28043007 | 0.78 | MAPK1 (0.49) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL21129789 | 0.78 | GPR35 (0.48) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL204005 | 0.78 | TSHR (0.50) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL30140371 | 0.77 | MAPK1 (0.47) | MAPTMAPK1KDM4EPKMMEN1 | |
| SCHEMBL203087 | 0.77 | MAPT (0.64) | MAPTMAPK1KDM4EPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5844110-A | Synthetic triple helix-forming compound precursors | UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) | 1998-12-01 | — | — | US | disclosed |
| WO-1997037999-A1 | SYNTHETIC TRIPLE HELIX-FORMING COMPOUNDS | UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) | 1997-10-16 | — | — | WO | disclosed |
| WO-1996023777-A1 | SYNTHETIC TRIPLE HELIX-FORMING COMPOUNDS | UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) | 1996-08-08 | — | — | WO | disclosed |