Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680478 | 0.90 | CES2 (0.50) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL3176121 | 0.90 | CES2 (0.56) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL10563656 | 0.87 | CES2 (0.46) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL8755031 | 0.87 | CES2 (0.46) | CES2CES1HTTDPP4SMN1; SMN2 | |
| SCHEMBL8726566 | 0.87 | CES2 (0.46) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL3345203 | 0.84 | CES2 (0.42) | CES2CES1HTTDPP4SMN1; SMN2 | |
| SCHEMBL26364830 | 0.84 | CES2 (0.48) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL2916433 | 0.82 | CES2 (0.52) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL20529620 | 0.80 | CES2 (0.50) | CES2CES1HTTDPP4MEN1 | |
| SCHEMBL16122048 | 0.79 | CES2 (0.54) | CES2CES1HTTDPP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739388-A | Process for the preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138023-A | Process for preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids | HOECHST AG (DE) | 1996-12-18 | — | — | CN | disclosed |