SCHEMBL8679258

SCHEMBL8679258

CCC(C)c1cccc(-c2ccccc2)c1C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 10/20 0.49
PDCD1 Q15116 8/20 0.49
TSHR P16473 1/20 0.48
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TRPA1 O75762 1/20 0.35
KCNQ2 O43526 1/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8683360 0.86 TSHR (0.44) CD274PDCD1TSHRCYP1A2CYP3A4
SCHEMBL5551237 0.85 TSHR (0.55) CD274PDCD1TSHRTRPA1KCNQ2
Ethane SCHEMBL5663955 0.83 TSHR (0.53) CD274PDCD1TSHRTRPA1KCNQ2
SCHEMBL11208110 0.83 PDCD1 (0.46) CD274PDCD1TRPA1
SCHEMBL8679944 0.82 TSHR (0.48) CD274PDCD1TSHRTRPA1KCNQ2
SCHEMBL28893488 0.81 TSHR (0.52) CD274PDCD1TSHRTRPA1KCNQ2
SCHEMBL6318808 0.81 PDCD1 (0.50) CD274PDCD1TSHRCYP1A2CYP3A4
SCHEMBL16684738 0.81 TSHR (0.47) CD274PDCD1TSHRTRPA1KCNQ2
SCHEMBL18745640 0.80 TSHR (0.58) TSHRCYP1A2CYP3A4ATMKDM4E
Methane SCHEMBL28472323 0.79 TSHR (0.46) CD274PDCD1TSHRTRPA1KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed