Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184537 | 0.86 | PPARA (0.48) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL2985863 | 0.83 | SIGMAR1 (0.44) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL8679258 | 0.83 | CD274 (0.49) | PDCD1CD274TRPA1 | |
| SCHEMBL6546728 | 0.81 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL11210724 | 0.81 | SIGMAR1 (0.42) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL6318808 | 0.78 | PDCD1 (0.50) | PDCD1CD274SLC6A2PPARAPPARG | |
| SCHEMBL28115795 | 0.77 | TAAR1 (0.52) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL6546628 | 0.77 | TAAR1 (0.44) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL19682353 | 0.75 | CD274 (0.47) | PDCD1CD274CYP2A6 | |
| SCHEMBL6281487 | 0.75 | CD274 (0.47) | PDCD1CD274CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |