Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059021 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5488552 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7557446 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL15463347 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5476526 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL93258 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10357941 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7557842 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7557536 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Adipic Acid SCHEMBL8593869 | 1.00 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652352-B2 | Photoresponsive nanoparticles as light-driven nanoscale actuators | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-02-18 | — | — | US | disclosed |
| US-7687600-B2 | Invertible amphiphilic polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687600-B2 | Invertible amphiphilic polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2010-03-30 | — | — | US | disclosed |
| US-20070293669-A1 | Invertible amphiphilic polymers | UNIVERSITY OF MASSACHUSETTS | 2007-12-20 | — | — | US | disclosed |
| US-20070293669-A1 | Invertible amphiphilic polymers | UNIVERSITY OF MASSACHUSETTS | 2007-12-20 | — | — | US | disclosed |
| US-5830953-A | REACTING A CARBOXYLIC ACID WITH POLYVINYL ALCOHOL IN PRESENCE OF A BASE | FUJI PHOTO FILM CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293669-A1 | Invertible amphiphilic polymers | PHOSPHO1, INF2, AQP1 | TSHR 4059/4885ALDH1A1 4784/4885CYP3A4 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.