Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30094172 | 0.78 | IDO1 (0.50) | IDO1PDPK1CYP11B2HTR6RET | |
| SCHEMBL1117278 | 0.78 | IDO1 (0.50) | IDO1PDPK1CYP11B2HTR6RET | |
| SCHEMBL11671198 | 0.77 | SRD5A1 (0.55) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL10181685 | 0.76 | IDO1 (0.48) | IDO1PDPK1CYP11B2HTR6RET | |
| SCHEMBL790430 | 0.76 | IDO1 (0.48) | IDO1PDPK1CYP11B2HTR6RET | |
| Magnesium SCHEMBL31510119 | 0.75 | SRD5A1 (0.53) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL29263189 | 0.75 | IDO1 (0.52) | IDO1PDPK1CYP11B2HTR6RET | |
| SCHEMBL10633202 | 0.75 | IDO1 (0.52) | IDO1PDPK1CYP11B2HTR6RET | |
| SCHEMBL29793145 | 0.74 | HTR2A (0.54) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL440138 | 0.74 | HTR2A (0.54) | IDO1PDPK1CYP11B2RETHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770663-A | HOMO OR COPOLYMERIZING UNSATURATED MONOMER SELECTED FROM ALPHA-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND A ORGANOMETALLIC COMPOUND OF 1A, 2A AND 3B AS COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5654454-A | REDUCING UNSATURATED SUBSTITUENTS; USED FOR ADDITION POLYMERIZATION OF OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| EP-0745607-A2 | Metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |