Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL8679476

CCOCC.CCOCC.OCCO.OCCOCCO

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.77
TSHR P16473 4/20 0.62
MAPK1 P28482 2/20 0.62
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
THRB P10828 2/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CASP1 P29466 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLCO1B3 Q9NPD5 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL21633769 1.00 ALDH1A1 (0.77) ALDH1A1TSHRMAPK1MEN1KMT2A
Tetraethylene Glycol SCHEMBL23931240 0.97 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1MEN1KMT2A
Triethylene Glycol SCHEMBL28205410 0.97 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL7035660 0.97 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL16595 0.97 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL1727711 0.97 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL6329241 0.94 ALDH1A1 (0.68) ALDH1A1TSHRMAPK1MEN1KMT2A
Diethylene Glycol Monoethyl Ether SCHEMBL3259182 0.94 ALDH1A1 (0.78) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL7075084 0.94 ALDH1A1 (0.88) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL15525356 0.94 ALDH1A1 (0.88) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845977-A1 CLEAR COSMETIC GEL COMPOSITION Colgate-Palmolive Company (US) 1998-06-10 EP disclosed
WO-1997006777-A1 CLEAR COSMETIC GEL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-02-27 WO disclosed