Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ARG2 | P78540 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590267 | 1.00 | MAOB (0.68) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL15540038 | 1.00 | MAOB (0.68) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155054 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL1524697 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155055 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL8554597 | 0.82 | TDP1 (0.58) | TDP1TSHRGPR52 | |
| SCHEMBL8554601 | 0.82 | TDP1 (0.58) | TDP1TSHRGPR52 | |
| SCHEMBL221307 | 0.81 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL16291705 | 0.81 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL221306 | 0.81 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756114-A | INCLUDING A PESTICIDE THAT IS TOXIC TO A TERMITE'S GUT-DWELLING CELLULASE-PRODUCING PROTOZOA | PETERSON JAMES E (US) | 1998-05-26 | — | — | US | claimed |
| US-5756114-A | INCLUDING A PESTICIDE THAT IS TOXIC TO A TERMITE'S GUT-DWELLING CELLULASE-PRODUCING PROTOZOA | PETERSON JAMES E (US) | 1998-05-26 | — | — | US | disclosed |