Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GPR52 | Q9Y2T5 | 16/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554597 | 1.00 | TDP1 (0.58) | TDP1GPR52TSHR | |
| SCHEMBL7762164 | 0.88 | GPR52 (0.57) | TDP1GPR52 | |
| SCHEMBL9715286 | 0.88 | GPR52 (0.57) | TDP1GPR52 | |
| SCHEMBL7762166 | 0.88 | GPR52 (0.57) | TDP1GPR52 | |
| SCHEMBL2243796 | 0.86 | GPR52 (0.53) | TDP1GPR52TSHR | |
| SCHEMBL5974140 | 0.86 | GPR52 (0.53) | TDP1GPR52TSHR | |
| SCHEMBL13078847 | 0.86 | GPR52 (0.53) | TDP1GPR52TSHR | |
| SCHEMBL10375115 | 0.84 | TDP1 (0.50) | TDP1GPR52 | |
| SCHEMBL9734298 | 0.84 | TDP1 (0.50) | TDP1GPR52 | |
| SCHEMBL10375114 | 0.84 | TDP1 (0.50) | TDP1GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |