SCHEMBL8679805

SCHEMBL8679805

CC(O)CN1CC(C)N(CC(C)O)CC1C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
SLC6A3 Q01959 2/20 0.32
KCNH2 Q12809 2/20 0.32
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
PIK3CD O00329 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095116 0.97
SCHEMBL4816224 0.79 MEN1 (0.35) SMN1; SMN2TSHR
SCHEMBL31237863 0.79 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL277608 0.79 MEN1 (0.40) SMN1; SMN2SLC6A3KCNH2DRD2DRD3
SCHEMBL8680434 0.78 MEN1 (0.40) SMN1; SMN2SLC6A3KCNH2DRD2DRD3
SCHEMBL1996123 0.76
SCHEMBL8406283 0.75 PIK3CD (0.31) SMN1; SMN2PIK3CDSIGMAR1
SCHEMBL25139395 0.75 SMN1; SMN2 (0.35) SMN1; SMN2
SCHEMBL10958661 0.73 CHRM1 (0.40) SMN1; SMN2DRD3PIK3CD
SCHEMBL23680491 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5709737-A AQUEOUS LIQUID VEHICLE, COLORANT, ALCOHOL ADDITIVE; SUITABLE FOR MICROWAVE DRYING PROCESSES XEROX CORPORATION (US) 1998-01-20 US claimed
US-5128408-A Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin TOYO BOSEKI KABUSHIKI KAISHA (JP) 1992-07-07 US disclosed
EP-0201340-B1 TONER COMPOSITION AND METHOD FOR PREPARING THE SAME Kao Corporation (JP) 1992-04-01 EP disclosed
EP-0250967-B1 PROCESS FOR THE PRODUCTION OF OLIGOESTERS BEARING HYDROXYLGROUPS AND THEIR APPLICATION BAYER AG (DE) 1991-07-10 EP disclosed
US-4757097-A Reacting non-halogenated cyclic dicarboxylic acid anhydride with alcohols or alkanolamines, alkoxylating reaction product BAYER AKTIENGESELLSCHAFT (DE) 1988-07-12 US disclosed
US-4749638-A CARBON BLACK, DISPERSANT, POLYMERIC BINDER OIL PHASE EMULSION POLYMERIZATION KAO CORPORATION (JP) 1988-06-07 US disclosed
EP-0201340-A2 Toner composition and method for preparing the same Kao Corporation (JP) 1986-11-12 EP disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed
US-4187112-A Photosensitive plate containing nitrogen containing condensation type polyesters TOYOBO CO., LTD. (JP) 1980-02-05 US disclosed
US-4096123-A COPOLYMER CONTAINING A TERTIARY AMINO GROUP TOYO BOSEKI KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed
US-4092316-A Synthesis of C-alkyl-triethylenediamines TEXACO DEVELOPMENT CORPORATION (US) 1978-05-30 US disclosed