⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816224 | 0.87 | MEN1 (0.35) | — | |
| SCHEMBL7499955 | 0.78 | DRD2 (0.45) | — | |
| SCHEMBL25139395 | 0.77 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL31237863 | 0.77 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL13144671 | 0.77 | LMNA (0.47) | — | |
| SCHEMBL32677707 | 0.76 | GPR84 (0.34) | — | |
| SCHEMBL7095116 | 0.75 | — | — | |
| SCHEMBL24292476 | 0.74 | MAPT (0.52) | — | |
| SCHEMBL10005738 | 0.73 | MAPT (0.37) | — | |
| SCHEMBL3832648 | 0.73 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093787-B1 | (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO NETHERLANDS BV (NL) | 2023-10-11 | — | — | EP | disclosed |
| EP-4093729-B1 | PARTICLES OF (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO NETHERLANDS BV (NL) | 2023-10-11 | — | — | EP | disclosed |
| WO-2021148558-A1 | (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021148556-A1 | PARTICLES OF (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |