SCHEMBL8680238

SCHEMBL8680238

CN1c2ccccc2C(C)(C)C12C=Cc1ccc3ccccc3c1O2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.55
GAA P10253 5/20 0.55
LMNA P02545 5/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
NPSR1 Q6W5P4 3/20 0.55
RECQL P46063 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
ALOX15 P16050 2/20 0.55
ALPG P10696 1/20 0.55
TP53 P04637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
KDM4E B2RXH2 8/20 0.54
THRB P10828 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
ALOX12 P18054 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
PKM P14618 2/20 0.54
ALDH1A1 P00352 5/20 0.43
HTT P42858 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10418903 0.86 MAPT (0.43) MAPTGAALMNAMEN1KMT2A
SCHEMBL10595643 0.85 MAPT (0.48) MAPTGAALMNAMEN1KMT2A
SCHEMBL14190054 0.83 MAPT (0.50) MAPTGAALMNAMEN1KMT2A
SCHEMBL25973516 0.81 MEN1 (0.47) MAPTGAALMNAMEN1KMT2A
SCHEMBL8680202 0.81 MAPT (0.51) MAPTGAALMNAMEN1KMT2A
SCHEMBL8682033 0.81 MAPT (0.56) MAPTGAALMNAMEN1KMT2A
SCHEMBL29848328 0.81 MAPT (0.63) MAPTGAALMNAMEN1KMT2A
SCHEMBL8681206 0.81 MAPT (0.55) MAPTGAALMNAMEN1KMT2A
SCHEMBL29931020 0.81 MAPT (0.63) MAPTGAALMNAMEN1KMT2A
SCHEMBL1894170 0.81 MAPT (0.63) MAPTGAALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
EP-0390869-A4 ORGANIC PHOTOCHROMIC PIGMENT 1990-11-07 EP disclosed
EP-0390869-A1 ORGANIC PHOTOCHROMIC PIGMENT PPG INDUSTRIES, INC. (US) 1990-10-10 EP disclosed
US-4880667-A SUNGLASSES, SPIROINDOLINE PHOTOCHROMIC COMPOUND PPG INDUSTRIES, INC. (US) 1989-11-14 US disclosed
WO-1989005464-A1 ORGANIC PHOTOCHROMIC PIGMENT PPG INDUSTRIES, INC. (US) 1989-06-15 WO disclosed