SCHEMBL8680332

SCHEMBL8680332

COc1cc([N+](=O)[O-])c(Br)c2c1OC1(C=C2)N(N(C)C)c2ccccc2C1(C)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8682560 0.91 MEN1 (0.30) MEN1KMT2A
SCHEMBL8685178 0.90 SMN1; SMN2 (0.33) MEN1KMT2A
SCHEMBL8682111 0.83 SMN1; SMN2 (0.34) MEN1KMT2A
SCHEMBL8680544 0.83 SMN1; SMN2 (0.33) MEN1KMT2A
SCHEMBL8680353 0.82 MAPK1 (0.33) MEN1KMT2A
SCHEMBL8680131 0.81 MAPT (0.42) MEN1KMT2A
SCHEMBL30612737 0.81 MAPT (0.42) MEN1KMT2A
SCHEMBL8680619 0.80 MAPT (0.34) MEN1KMT2A
SCHEMBL8681128 0.80 MAPT (0.33) MEN1KMT2A
SCHEMBL8679966 0.80 LMNA (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed