Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677290 | 0.84 | TLR7 (0.43) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8678948 | 0.82 | TLR7 (0.44) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8678462 | 0.81 | L3MBTL1 (0.45) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8680418 | 0.81 | TLR7 (0.43) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8678391 | 0.80 | TLR7 (0.43) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8680415 | 0.79 | TLR7 (0.42) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8678060 | 0.79 | TLR7 (0.42) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8678382 | 0.77 | TLR7 (0.43) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8680675 | 0.77 | L3MBTL1 (0.41) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8137227 | 0.76 | CYP1A2 (0.43) | TLR7L3MBTL1SMN1; SMN2LMNAPTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |