Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467742 | 0.90 | LMNA (0.55) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL867792 | 0.79 | LMNA (0.55) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL2980323 | 0.79 | LMNA (0.55) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL2982475 | 0.79 | LMNA (0.55) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL10703486 | 0.78 | LMNA (0.46) | LMNAF2TSHRALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL5809891 | 0.77 | LMNA (0.54) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL10340068 | 0.77 | LMNA (0.57) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL17167697 | 0.77 | LMNA (0.52) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL9305857 | 0.76 | LMNA (0.81) | LMNAF2TSHRALDH1A1TDP1 | |
| SCHEMBL991333 | 0.75 | LMNA (0.80) | LMNAF2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5738745-A | COMPOUNDING MIXTURE OF TWO THERMOPLASTIC POLYPROPYLENE RESINS OF DIFFERENT MOLECULAR WEIGHTS WITH PHOTOSTABILIZER | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-04-14 | — | — | US | disclosed |