Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8679384 | 0.92 | TSHR (0.67) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL16765797 | 0.90 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL20609794 | 0.90 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL29596375 | 0.90 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL14869 | 0.90 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL8678917 | 0.89 | TSHR (0.64) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Ethylene Glycol SCHEMBL19639819 | 0.88 | TSHR (0.91) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Ethylene Glycol SCHEMBL20838524 | 0.88 | TSHR (0.91) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Bromide SCHEMBL20490069 | 0.88 | TSHR (0.97) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL10432463 | 0.88 | TSHR (0.97) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820478-A1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEMICAL COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |