Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL7263337 | 0.92 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid SCHEMBL3844152 | 0.92 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL8680403 | 0.92 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL8679381 | 0.88 | TSHR (0.71) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL338002 | 0.88 | TSHR (0.88) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid Methyl Ester SCHEMBL5718144 | 0.87 | TSHR (0.72) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid SCHEMBL29291566 | 0.87 | TSHR (0.76) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid SCHEMBL2282780 | 0.86 | TSHR (0.91) | TSHRHPGDCYP3A4TDP1ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL9863764 | 0.84 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL17139830 | 0.84 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820478-A1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEMICAL COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |