Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259652 | 1.00 | ALDH1A1 (0.55) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL6263207 | 0.98 | ALDH1A1 (0.53) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL16167161 | 0.95 | FOLH1 (0.50) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL131266 | 0.88 | ALDH1A1 (0.55) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL31073993 | 0.88 | ALDH1A1 (0.55) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL26597207 | 0.87 | ALDH1A1 (0.48) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL3526217 | 0.87 | FOLH1 (0.53) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL10629058 | 0.87 | CYSLTR2 (0.56) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL27681648 | 0.87 | CYP3A4 (0.51) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL15512121 | 0.87 | ALDH1A1 (0.57) | ALDH1A1FOLH1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739619-B1 | Foaming o/w emulsion based on non-ionic surfactants, a fatty phase and a cross-linked cationic or anionic polymer for topical use | OREAL (FR) | 1998-01-14 | — | — | EP | claimed |
| EP-2665463-B1 | ANTIPERSPIRANT STICK WITH IMPROVED LONG-TERM STABILITY | HENKEL AG & CO KGAA (DE) | 2017-06-28 | — | — | EP | disclosed |
| EP-2665463-A2 | ANTIPERSPIRANT STICK WITH IMPROVED LONG-TERM STABILITY | Henkel AG & Co. KGaA (DE) | 2013-11-27 | — | — | EP | disclosed |
| WO-2013144121-A2 | ANTIPERSPIRANT COMPOUNDS COMPRISING CYCLOALIPHATIC DIOLS AND ZIRCONIUM SALTS | HENKEL AG & CO. KGAA (DE) | 2013-10-03 | — | — | WO | disclosed |
| WO-2012098189-A2 | ANTIPERSPIRANT STICK WITH IMPROVED LONG-TERM STABILITY | HENKEL AG & CO. KGAA (DE) | 2012-07-26 | — | — | WO | disclosed |