SCHEMBL8680755

SCHEMBL8680755

CC1=Cc2c(ccc3ccccc23)OC12N(C)c1ccccc1C2(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.51
KDM4E B2RXH2 10/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
THRB P10828 4/20 0.51
ALOX12 P18054 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
PKM P14618 1/20 0.51
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 6/20 0.41
GAA P10253 5/20 0.41
LMNA P02545 5/20 0.41
HPGD P15428 4/20 0.41
HTT P42858 3/20 0.41
RECQL P46063 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
NPSR1 Q6W5P4 3/20 0.37
ALOX15 P16050 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680284 0.77 MAPT (0.43) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL1894170 0.76 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL29931020 0.76 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL29848328 0.76 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL29637641 0.75 MAPT (0.59) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL8680702 0.74 ALDH1A1 (0.40) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL8680360 0.71 MAPT (0.59) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL8680280 0.71 SMN1; SMN2 (0.45) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL8685339 0.70 MAPT (0.37) MAPTKDM4ESMN1; SMN2THRBALOX12
SCHEMBL8684924 0.68 MAPT (0.50) MAPTKDM4ESMN1; SMN2THRBALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed