SCHEMBL8680757

SCHEMBL8680757

O=Nc1ccccc1NO.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.38
LMNA P02545 3/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
IDO1 P14902 1/20 0.33
SIGMAR1 Q99720 6/20 0.33
GRIN2D O15399 3/20 0.33
GRIN3B O60391 3/20 0.33
GRIN1 Q05586 3/20 0.33
GRIN2A Q12879 3/20 0.33
GRIN2B Q13224 3/20 0.33
GRIN2C Q14957 3/20 0.33
GRIN3A Q8TCU5 3/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ALOX15 P16050 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105074 0.98 HTT (0.39) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL106000 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL21670425 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL101947 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL1815831 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
Hydrochloric Acid SCHEMBL1719169 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL8677252 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL21670429 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
Ammonia Solution, Strong SCHEMBL103629 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1
SCHEMBL105654 0.95 HTT (0.38) HTTLMNAALDH1A1HSD17B10IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108993765-B Method for flotation separation of tantalum, niobium and spodumene from spodumene concentrate containing tantalum and niobium 广东省资源综合利用研究所 2020-07-28 CN claimed
US-5824195-A USING N-NITROSOPHENYLHYDROXYLAMINE SALT AND/OR COPPER DIALKYLDITHIOCARBAMATE SYNERGISTIC MIXTURE AS POLYMERIZATION INHIBITORS CHISSO CORPORATION (JP) 1998-10-20 US disclosed
EP-0753521-A2 Process for distilling crude acrylic silane solution Chisso Corporation (JP) 1997-01-15 EP disclosed