Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686117 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8683105 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8680821 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8680924 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8680978 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8681006 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8683114 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8681074 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8682077 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 | |
| SCHEMBL8686053 | 1.00 | NAAA (0.47) | NAAAL3MBTL1NPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |