SCHEMBL8680835

SCHEMBL8680835

CCCCCCCC(CCC(Cl)C(=O)NNc1ccccc1)Oc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.44
XBP1 P17861 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HDAC8 Q9BY41 6/20 0.36
HDAC3 O15379 4/20 0.36
HDAC6 Q9UBN7 3/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC2 Q92769 3/20 0.36
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
ESRRA P11474 2/20 0.34
HDAC4 P56524 2/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11581031 0.77 GAA (0.50) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL10474806 0.77 GAA (0.51) GAAHDAC8HDAC3HDAC6HDAC1
SCHEMBL8152752 0.72 ATM (0.58) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL10447397 0.72 GAA (0.41) GAAHDAC8HDAC3HDAC6HDAC1
SCHEMBL11772389 0.72 ATM (0.53) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL11772401 0.72 ATM (0.53) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL10439329 0.72 GAA (0.46) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL9186566 0.70 ATM (0.54) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL4637888 0.70 ATM (0.58) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL9730892 0.70 GAA (0.44) GAAXBP1ATMNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736299-A A PYRROLOAZOLE CYAN COUPLER TO IMPROVE STORAGE STABILITY AND HEAT RESISTANCE; NONMIXING OF COLORS (COLOR TURBIDITY) IN A COLOR REVERSAL PROCESS HAVING HIGHLY-BASIC DEVELOPING SOLUTION; REPRODUCTION; ANTISOILANTS; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1998-04-07 US disclosed