SCHEMBL10447397

SCHEMBL10447397

CCCCCCCCCCC(Oc1ccc(O)cc1C(C)(C)C)C(=O)NNc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.41
HDAC8 Q9BY41 6/20 0.39
HDAC3 O15379 4/20 0.39
HDAC6 Q9UBN7 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC4 P56524 2/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
SIRT2 Q8IXJ6 3/20 0.37
SIRT1 Q96EB6 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447396 0.84 CYSLTR2 (0.36) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL9738522 0.81 CYSLTR2 (0.39) GAAALDH1A1CYSLTR2CYSLTR1THRA
SCHEMBL8421006 0.78 NPC1 (0.41) GAAALDH1A1LMNAPKMUBLCP1
SCHEMBL8421004 0.78 ADCY6 (0.38) GAAALDH1A1LMNAPKMUBLCP1
SCHEMBL11581031 0.73 GAA (0.50) GAAHDAC8HDAC3HDAC6HDAC1
SCHEMBL8680835 0.72 GAA (0.44) GAAHDAC8HDAC3HDAC6HDAC1
SCHEMBL9474768 0.71 CTRC (0.49)
SCHEMBL25350721 0.70 ALOX15 (0.50) SMN1; SMN2CYSLTR2CYSLTR1THRATHRB
SCHEMBL28138095 0.70 ALOX15 (0.50) SMN1; SMN2CYSLTR2CYSLTR1THRATHRB
SCHEMBL9474764 0.69 CTRC (0.45) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362808-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed