Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681176 | 0.95 | FAAH (0.44) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8680888 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8686103 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8682013 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8682086 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8680766 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8685986 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8681039 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8680958 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL8681387 | 0.94 | FAAH (0.47) | FAAHCNR1CNR2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |