Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.52 |
| ▸ | ITGAV | P06756 | 20/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683388 | 0.89 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL8681923 | 0.89 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL8682242 | 0.87 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL8684527 | 0.86 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL8682045 | 0.86 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL8684581 | 0.86 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL8687829 | 0.86 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL8682642 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL8682166 | 0.79 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982741 | 0.79 | ITGB3 (0.59) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |