Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681178 | 1.00 | NAAA (0.41) | NAAAEPHX1TSHREPHX2GAA | |
| SCHEMBL8682191 | 1.00 | NAAA (0.41) | NAAAEPHX1TSHREPHX2GAA | |
| SCHEMBL8682098 | 1.00 | NAAA (0.41) | NAAAEPHX1TSHREPHX2GAA | |
| SCHEMBL8683098 | 1.00 | NAAA (0.41) | NAAAEPHX1TSHREPHX2GAA | |
| SCHEMBL8681070 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL8686113 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL8680776 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL8683097 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL8680921 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL8680816 | 0.96 | NAAA (0.41) | NAAAEPHX1TSHRGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |