Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681710 | 0.99 | MCHR1 (0.40) | HTR1AMCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8681457 | 0.99 | MCHR1 (0.40) | HTR1AMCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8681755 | 0.99 | MCHR1 (0.40) | HTR1AMCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8686595 | 0.87 | PPARG (0.38) | HTR1AMCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL11340769 | 0.82 | MEN1 (0.38) | HTR1AMCHR1ALDH1A1KMT2APDE4A | |
| SCHEMBL8681543 | 0.81 | ALOX5AP (0.36) | HTR1AAPP | |
| SCHEMBL8686869 | 0.81 | KDM4E (0.43) | MCHR1ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL8681729 | 0.80 | PPARG (0.39) | HTR1AMCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8682986 | 0.80 | KDM4E (0.45) | MCHR1ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL8681490 | 0.80 | ALOX5AP (0.35) | HTR1AMCHR1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780194-A | PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |