Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681710 | 0.84 | MCHR1 (0.40) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL8681755 | 0.84 | MCHR1 (0.40) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL8681457 | 0.84 | MCHR1 (0.40) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL8683045 | 0.82 | HTR1A (0.39) | KMT2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1803614 | 0.77 | LMNA (0.51) | MEN1KMT2ACYP2C9KCNH2ALDH1A1 | |
| SCHEMBL8686595 | 0.75 | PPARG (0.38) | KMT2AMCHR1PTGDR2HTR1AALDH1A1 | |
| SCHEMBL28000803 | 0.75 | LMNA (0.53) | MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL3390002 | 0.73 | ACMSD (0.53) | ACMSD | |
| SCHEMBL10647655 | 0.73 | ACHE (0.43) | ADRB2CYP2C19ADRB1ADRB3PTGS1 | |
| SCHEMBL22313381 | 0.73 | LMNA (0.40) | PDE4BPDE4APDE4CPDE4DACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |