Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL29573098 | 0.92 | TSHR (0.65) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL321169 | 0.92 | TSHR (0.65) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL5334646 | 0.92 | TSHR (0.65) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL675043 | 0.92 | TSHR (0.65) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL28663674 | 0.89 | TSHR (0.61) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL28661396 | 0.89 | TSHR (0.61) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL28659856 | 0.89 | TSHR (0.61) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL1533980 | 0.89 | TSHR (0.61) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL28356942 | 0.86 | TSHR (0.58) | TSHRCA2CA4CA5APBRM1 | |
| Aniline SCHEMBL27905075 | 0.86 | TSHR (0.58) | TSHRCA2CA4CA5APBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000564-A1 | METHODS AND COMPOSITIONS FOR SEQUENCE-SPECIFIC HYBRIDIZATION OF RNA BY 2'-5' OLIGONUCLEOTIDES | DYAD PHARMACEUTICAL CORPORATION (US) | 1998-01-08 | — | — | WO | claimed |
| US-5532130-A | HYBRIDIZING SINGLE STRAND DNA FOR ANTISENSE OLIGONUCLEOTIDES | DYAD PHARMACEUTICAL CORPORATION (US) | 1996-07-02 | — | — | US | claimed |