Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139905 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20774476 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854574 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854579 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854578 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL21660228 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854584 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854575 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL20854580 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG | |
| SCHEMBL8863059 | 0.83 | CES2 (0.52) | CES2CES1TSHRGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716626-A | MIXTURE CONTAINING A PHOSPHATE, SULFATE AND/OR SULFONATE ANIONIC SURFACTANT AND A NONIONIC SURFACTANT | KAO CORPORATION (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0728475-A2 | Skin cleanser | KAO CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |