Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682485 | 1.00 | HTR1A (0.45) | HTR1APOLBSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8681910 | 1.00 | HTR1A (0.45) | HTR1APOLBSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8686934 | 0.98 | HTR1A (0.46) | HTR1APOLBSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8683743 | 0.81 | EPHX2 (0.40) | SMN1; SMN2ALOX5APFEN1KDM4EHIF1A | |
| SCHEMBL8686944 | 0.81 | EPHX2 (0.40) | SMN1; SMN2ALOX5APFEN1KDM4EHIF1A | |
| SCHEMBL8681799 | 0.81 | EPHX2 (0.40) | SMN1; SMN2ALOX5APFEN1KDM4EHIF1A | |
| SCHEMBL16559623 | 0.81 | ALOX5AP (0.34) | HTR1ASMN1; SMN2HTTALDH1A1ALOX5AP | |
| SCHEMBL8681855 | 0.80 | ALOX5AP (0.35) | HTR1APOLBALDH1A1ALOX5APFEN1 | |
| SCHEMBL8681490 | 0.80 | ALOX5AP (0.35) | HTR1APOLBALDH1A1ALOX5APFEN1 | |
| SCHEMBL8682986 | 0.80 | KDM4E (0.45) | SMN1; SMN2ALDH1A1KDM4EPTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780194-A | PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |