Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682801 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BITGAVHTRA1METTL3 | |
| SCHEMBL8683601 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BITGAVANPEPHTRA1 | |
| SCHEMBL8682279 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BITGAVHTRA1METTL3 | |
| Hydrochloric Acid SCHEMBL8682425 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHTRA1METTL3 | |
| SCHEMBL8683338 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BITGAVANPEPHTRA1 | |
| SCHEMBL8683577 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BITGAVANPEPHTRA1 | |
| SCHEMBL8682266 | 0.83 | HTRA1 (0.38) | ITGB3ITGA2BITGAVHTRA1METTL3 | |
| SCHEMBL8682751 | 0.83 | ITGB3 (0.36) | ITGB3ITGA2BITGAVMETTL3ITGB1 | |
| Trifluoroacetic Acid SCHEMBL8684118 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BITGAVHTRA1METTL3 | |
| Trifluoroacetic Acid SCHEMBL8681427 | 0.81 | ITGB3 (0.45) | ITGB3ITGA2BITGAVANPEPHTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |