Sugi Predict

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SCHEMBL8683228

SCHEMBL8683228

CCOC(=O)Cn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccc(/C=N/OCc4ccccc4)c3)cc21

nearest known ligand 0.85

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GRIA1 P42261 15/20 0.85
▸ GRIA2 P42262 15/20 0.85
▸ GRIA3 P42263 15/20 0.85
▸ GRIA4 P48058 15/20 0.85
▸ GRIK1 P39086 8/20 0.54
▸ GRIK2 Q13002 8/20 0.54
▸ GRIK3 Q13003 8/20 0.54
▸ GRIK4 Q16099 8/20 0.54
▸ GRIK5 Q16478 8/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8683231 1.00 GRIA1 (0.85) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8611625 0.92 GRIA1 (1.00) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8611628 0.92 GRIA1 (1.00) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8612872 0.87 GRIA1 (0.75) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8612870 0.87 GRIA1 (0.75) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL7668608 0.84 GRIA1 (0.78) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8610465 0.83 GRIA1 (0.73) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL7480169 0.81 GRIA1 (0.71) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL7665861 0.81 GRIA1 (0.78) GRIA1GRIA2GRIA3GRIA4GRIK1
SCHEMBL8609954 0.81 GRIA1 (0.78) GRIA1GRIA2GRIA3GRIA4GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5852017-A 2,3(1H,4H)-quinoxalinediones BASF AKTIENGESELLSCHAFT (DE) 1998-12-22 — — US disclosed