Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373801 | 0.81 | RXFP1 (0.72) | RXFP1KMT2AMEN1NPC1ATM | |
| Bamifylline SCHEMBL219043 | 0.79 | RXFP1 (0.60) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL682786 | 0.78 | RXFP1 (0.65) | RXFP1KMT2AMEN1NPC1ATM | |
| Bamifylline SCHEMBL637064 | 0.78 | RXFP1 (0.58) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| Bamifylline SCHEMBL1648640 | 0.77 | RXFP1 (0.57) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL3099603 | 0.75 | RXFP1 (1.00) | RXFP1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL684310 | 0.75 | RXFP1 (0.66) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| Bamifylline SCHEMBL27460692 | 0.74 | RXFP1 (0.53) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| Bamifylline SCHEMBL28086377 | 0.72 | TSHR (0.53) | RXFP1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL19829270 | 0.72 | TSHR (0.64) | RXFP1KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739331-A | PREPARING BAMIFYLLINE AND ETAMIPHYLLINE | S.A. NYCOMED CHRISTIAENS N.V. (BE) | 1998-04-14 | — | — | US | disclosed |