SCHEMBL8683418

SCHEMBL8683418

CCCCCCCCC(Oc1ccc(O)c(C(C)(C)C)c1)C(=O)Nc1ccc(Cl)c([NH])c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRA P11474 2/20 0.45
GAA P10253 1/20 0.45
XBP1 P17861 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ADCY6 O43306 2/20 0.44
ADCY3 O60266 2/20 0.44
ADCY9 O60503 2/20 0.44
ADCY5 O95622 2/20 0.44
ADCY8 P40145 2/20 0.44
GCGR P47871 2/20 0.44
ADCY7 P51828 2/20 0.44
ADCY2 Q08462 2/20 0.44
ADCY1 Q08828 2/20 0.44
ADCY4 Q8NFM4 2/20 0.44
NR1H4 Q96RI1 12/20 0.42
LMNA P02545 1/20 0.37
RORC P51449 1/20 0.36
THRA P10827 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8101980 1.00 ESRRA (0.45) ESRRAGAAXBP1ATMNPSR1
SCHEMBL2449481 1.00 ESRRA (0.45) ESRRAGAAXBP1ATMNPSR1
SCHEMBL8683421 0.89 ESRRA (0.45) ESRRAGAAXBP1ATMNPSR1
SCHEMBL8101982 0.89 ESRRA (0.45) ESRRAGAAXBP1ATMNPSR1
SCHEMBL2449483 0.89 ESRRA (0.45) ESRRAGAAXBP1ATMNPSR1
SCHEMBL9193654 0.88 GAA (0.48) ESRRAGAAXBP1ATMNPSR1
SCHEMBL11367539 0.85 ADCY6 (0.44) GAAL3MBTL1ADCY6ADCY3ADCY9
SCHEMBL8421004 0.85 ADCY6 (0.38) ESRRAGAAADCY6ADCY3ADCY9
SCHEMBL11333334 0.84 ADCY6 (0.48) ADCY6ADCY3ADCY9ADCY5ADCY8
SCHEMBL10336885 0.84 GAA (0.44) ESRRAGAAXBP1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753424-A CONTAINING FERROMAGNETIC POWDER AND AROMATIC SULFONATE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1998-05-19 US disclosed