Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044359 | 0.92 | REN (0.53) | REN | |
| SCHEMBL6044137 | 0.92 | REN (0.55) | REN | |
| SCHEMBL6044816 | 0.92 | REN (0.56) | REN | |
| SCHEMBL8683037 | 0.89 | REN (0.55) | REN | |
| SCHEMBL6045113 | 0.88 | REN (0.57) | REN | |
| SCHEMBL6045049 | 0.88 | REN (0.56) | REN | |
| SCHEMBL6044314 | 0.88 | REN (0.57) | REN | |
| SCHEMBL6044215 | 0.88 | REN (0.57) | REN | |
| SCHEMBL6045404 | 0.88 | REN (0.58) | REN | |
| SCHEMBL6044227 | 0.88 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705658-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-01-06 | — | — | US | disclosed |
| US-5646143-A | FOR TREATING A VARIETY OF CONDITIONS | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5627182-A | RENIN INHIBITORS FOR USE AS HYPOTENSIVE AGENTS | CIBA GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |