Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881403 | 0.73 | NFE2L2 (0.55) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL1881401 | 0.73 | NFE2L2 (0.55) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL20037028 | 0.71 | NFE2L2 (0.52) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL8684384 | 0.68 | — | — | |
| SCHEMBL9245245 | 0.68 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL9245251 | 0.68 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL14757680 | 0.67 | — | — | |
| SCHEMBL37097 | 0.67 | — | — | |
| SCHEMBL37098 | 0.67 | — | — | |
| SCHEMBL17333247 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716974-A | TREATING FUNGAL PLANT DISEASES | ISAGRO S.P.A. (IT) | 1998-02-10 | — | — | US | claimed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | claimed |
| US-5716974-A | TREATING FUNGAL PLANT DISEASES | ISAGRO S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | disclosed |