Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641177 | 0.89 | EDNRA (0.46) | EDNRAEDNRB | |
| SCHEMBL8687989 | 0.88 | EDNRA (0.40) | EDNRAEDNRB | |
| SCHEMBL8684450 | 0.88 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL8684550 | 0.88 | EDNRA (0.36) | EDNRAEDNRB | |
| SCHEMBL8684652 | 0.86 | EDNRA (0.37) | EDNRAEDNRB | |
| SCHEMBL15703456 | 0.85 | MAPT (0.35) | — | |
| SCHEMBL6700336 | 0.82 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL8685255 | 0.80 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL4773487 | 0.78 | EDNRB (0.35) | EDNRAEDNRB | |
| SCHEMBL30757333 | 0.78 | EDNRA (0.37) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780473-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998004260-A1 | SUBSTITUTED BIPHENYL SULFONAMIDE ENDOTHELIN ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |