Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684450 | 0.91 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL8684550 | 0.91 | EDNRA (0.36) | EDNRAEDNRB | |
| SCHEMBL8684591 | 0.86 | EDNRA (0.35) | EDNRAEDNRB | |
| SCHEMBL8685255 | 0.84 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL6646134 | 0.81 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL6638557 | 0.81 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL8685211 | 0.79 | EDNRA (0.41) | EDNRAEDNRB | |
| SCHEMBL30171050 | 0.78 | EDNRA (0.36) | EDNRAEDNRB | |
| SCHEMBL30171242 | 0.77 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL29001525 | 0.77 | EDNRA (0.38) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780473-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-14 | — | — | US | disclosed |