Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524180 | 1.00 | LMNA (0.60) | LMNAAOC3ADRB2GAABRD4 | |
| SCHEMBL3930111 | 1.00 | LMNA (0.60) | LMNAAOC3ADRB2GAABRD4 | |
| SCHEMBL11312030 | 0.94 | LMNA (0.54) | LMNAAOC3ADRB2GAABRD4 | |
| SCHEMBL9607479 | 0.88 | LMNA (0.48) | LMNAAOC3GAASMN1; SMN2 | |
| SCHEMBL1607138 | 0.87 | LMNA (0.75) | LMNAAOC3SMN1; SMN2PGRTSHR | |
| SCHEMBL4035560 | 0.83 | LMNA (0.62) | LMNAAOC3SMN1; SMN2HTTPGR | |
| Phenylpropanol SCHEMBL27591198 | 0.83 | LMNA (0.76) | LMNAAOC3TSHRSLC6A2SLC6A4 | |
| SCHEMBL6690160 | 0.82 | AOC3 (0.53) | LMNAAOC3ADRB2GAABRD4 | |
| SCHEMBL9772644 | 0.82 | AOC3 (0.53) | LMNAAOC3ADRB2GAABRD4 | |
| SCHEMBL9772894 | 0.82 | AOC3 (0.53) | LMNAAOC3ADRB2GAABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117682951-A | Method for preparing diphenyl aryl ether ester derivative | 南京农业大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115215762-B | Method for synthesizing aliphatic nitrile from alcohol | 陕西师范大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114890899-B | Method for preparing diphenyl ether ester compound | 南京农业大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116640104-A | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023070996-A1 | DIPHENYL ETHER ESTER COMPOUND AND APPLICATION THEREOF, AND PESTICIDE BACTERICIDE | 南京农业大学 | 2023-05-04 | — | — | WO | disclosed |
| EP-3849968-B1 | 1H-INDAZOLE CARBOXAMIDES AS RECEPTOR-INTERACTING PROTEIN KINASE 1 INHIBITORS (RIPK1) | BRISTOL MYERS SQUIBB CO (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-115215762-A | Method for synthesizing aliphatic nitrile from alcohol | 陕西师范大学 | 2022-10-21 | — | — | CN | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0450995-B1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL SA (FR) | 1994-06-08 | — | — | EP | disclosed |
| US-5236947-A | Side effect reduction | JOUVEINAL S.A. (FR) | 1993-08-17 | — | — | US | disclosed |
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5143938-A | PROPANAMINES, THEIR PHARMACOLOGICAL PROPERTIES AND THEIR APPLICATION FOR THERAPEUTIC IN PARTICULAR ANTIDIARRHEAL, PURPOSES | JOUVEINAL S.A. (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0450995-A1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL S.A. (FR) | 1991-10-09 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4489094-A | Arylalkylaminobenzoic acids | AMERICAN CYANAMID COMPANY (US) | 1984-12-18 | — | — | US | disclosed |