SCHEMBL868474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL869284	0.90	RIPK1 (0.80)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL30500616	0.89	EIF2AK3 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL29384284	0.89	EIF2AK3 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL868254	0.89	EIF2AK3 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL29403654	0.89	EIF2AK3 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL868757	0.88	RIPK1 (0.77)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL868935	0.87	RIPK1 (0.75)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL869189	0.86	RIPK1 (0.82)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL870488	0.85	RIPK1 (0.81)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1
	SCHEMBL869982	0.83	RIPK1 (0.78)	RIPK1EIF2AK3EIF2AK2EIF2AK1NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.