SCHEMBL868484

SCHEMBL868484

O=Cc1ccccc1-c1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.57
HDAC4 P56524 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
BACE1 P56817 2/20 0.49
ERN1 O75460 2/20 0.48
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ACHE P22303 1/20 0.46
XDH P47989 1/20 0.45
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR2 Q92731 2/20 0.42
ESR1 P03372 1/20 0.42
CCNC P24863 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31406989 1.00 GSTP1 (0.57) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL31406988 1.00 GSTP1 (0.57) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL29048712 0.94 GSTP1 (0.50) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL12197265 0.86 HDAC4 (0.44) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL29518280 0.86 ERN1 (0.46) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL28729423 0.86 ERN1 (0.46) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL3911728 0.86 CYP2A6 (0.47) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL3967175 0.84 HDAC4 (0.61) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL28397477 0.84 HDAC4 (0.45) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL9914806 0.83 ERN1 (0.45) GSTP1HDAC4HDAC2HDAC8BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437143-B Benzyl substituted quinoline and derivative and synthesis method thereof 湘潭大学 2022-08-09 CN claimed
US-20130315834-A1 NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-11-28 US claimed
WO-2012039685-A1 A NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-29 WO claimed
US-12552779-B2 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2026-02-17 US disclosed
CN-119948083-A Curable composition 株式会社大赛璐 2025-05-06 CN disclosed
US-20240358679-A1 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) 2024-10-31 US disclosed
CN-111727525-B Lithium secondary battery 松下知识产权经营株式会社 2024-07-02 CN disclosed
CN-111684645-B Lithium secondary battery 松下知识产权经营株式会社 2024-06-07 CN disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
CN-117561581-A Insulated wire, coil including insulated wire, and cable 株式会社大赛璐 2024-02-13 CN disclosed
CN-112313284-B Curable composition 株式会社大赛璐 2023-11-03 CN disclosed
EP-0123842-B1 PHOTO-CURABLE EPOXY RESIN TYPE COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-19 EP disclosed
EP-0195846-A2 Photo-curable epoxy resin type composition and curing process KABUSHIKI KAISHA TOSHIBA (JP) 1986-10-01 EP disclosed
US-4599155-A POLYORTHOESTERS;SHRINKAGE INHIBITION;NONCRACKING;COATINGS KABUSHIKI KAISHA TOSHIBA (JP) 1986-07-08 US disclosed
EP-0172330-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-02-26 EP disclosed
EP-0139234-A2 Resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-05-02 EP disclosed
EP-0135887-A2 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-04-03 EP disclosed
EP-0123842-A1 Photo-curable epoxy resin type composition KABUSHIKI KAISHA TOSHIBA (JP) 1984-11-07 EP disclosed
EP-0114258-A1 Resin encapsulation type photo-semiconductor devices KABUSHIKI KAISHA TOSHIBA (JP) 1984-08-01 EP disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552779-B2 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases SNCA, HTT, PSEN1 GSTP1 279/4885HDAC4 377/4885HDAC2 164/4885
US-20130315834-A1 NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER CD47, ALB, HCCS GSTP1 296/4885HDAC4 4645/4885HDAC2 4722/4885
US-20240358679-A1 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES GPX4, GPX1, SELENOI GSTP1 138/4885HDAC4 163/4885HDAC2 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.