SCHEMBL8685175

SCHEMBL8685175

CC1=Cc2ccccc2OC12C=Cc1ccccc1O2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
TP53 P04637 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
UBE2N P61088 1/20 0.39
NPSR1 Q6W5P4 3/20 0.34
HTT P42858 1/20 0.34
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
XDH P47989 1/20 0.32
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
GAA P10253 2/20 0.30
LMNA P02545 1/20 0.30
ALPG P10696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11237452 0.85 HTR2C (0.47) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL11228286 0.85 HTR2C (0.33) HTR2CHTR2BMAPTMEN1TP53
SCHEMBL11586208 0.83 CA12 (0.35) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8680577 0.81 HTR2C (0.40) HTR2CHTR2BMAPTMEN1TP53
SCHEMBL8680285 0.80 MEN1 (0.41) HTR2CHTR2BMAPTMEN1TP53
SCHEMBL8680629 0.80 MEN1 (0.46) MAPTMEN1TP53KMT2ATSHR
SCHEMBL8682159 0.80 MEN1 (0.41) MAPTMEN1KMT2ATSHRHTT
SCHEMBL11392410 0.79 LMNA (0.35) MAPTMEN1TP53KMT2AMAPK1
SCHEMBL8685158 0.76 HTR2C (0.41) HTR2CHTR2BMAPTMEN1TP53
SCHEMBL8680342 0.75 TSHR (0.53) HTR2CHTR2BMAPTMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed