Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685750 | 0.88 | PIM1 (0.49) | PIM1GSK3AGSK3BUSP2HSD17B10 | |
| SCHEMBL8685620 | 0.84 | GSK3A (0.50) | PIM1GSK3AGSK3BGAAALDH1A1 | |
| SCHEMBL8691072 | 0.83 | PIM1 (0.72) | PIM1GSK3AGSK3BGAAKDM4E | |
| SCHEMBL8687928 | 0.83 | PIM1 (0.51) | PIM1GSK3AGSK3BALDH1A1CNR2 | |
| SCHEMBL8690593 | 0.82 | MAPT (0.46) | PIM1GSK3AGSK3BKDM4EALDH1A1 | |
| SCHEMBL8685916 | 0.82 | PIM1 (0.56) | PIM1GSK3AGSK3BALDH1A1TSHR | |
| SCHEMBL8686737 | 0.81 | PIM1 (0.49) | PIM1GSK3AGSK3BGAAALDH1A1 | |
| SCHEMBL8686647 | 0.80 | PIM1 (0.53) | PIM1GSK3AGSK3BALDH1A1TP53 | |
| SCHEMBL8685120 | 0.80 | PIM1 (0.60) | PIM1GSK3AGSK3BALDH1A1HTR2C | |
| SCHEMBL8686360 | 0.80 | GSK3A (0.48) | PIM1GSK3AGSK3BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |