Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MPC2 | O95563 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811224 | 0.82 | PPARG (0.47) | CA2PPARGFFAR1MAPTKCNH2 | |
| SCHEMBL8809682 | 0.82 | PPARG (0.42) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8812001 | 0.81 | PPARG (0.41) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8810162 | 0.81 | PPARG (0.44) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8810514 | 0.81 | PPARG (0.46) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL9570635 | 0.80 | MAPT (0.53) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8685774 | 0.80 | FFAR1 (0.50) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8813371 | 0.80 | PPARG (0.41) | CA2PPARGFFAR1MAOACISD1 | |
| SCHEMBL8686495 | 0.80 | PPARG (0.44) | CA2PPARGFFAR1MAPTKCNH2 | |
| SCHEMBL8685830 | 0.80 | PPARG (0.47) | CA2PPARGFFAR1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |